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Calcium supplements and heart attack risk


     Bone loss and fractures are a major health concern among older people. Ian Reid, professor of medicine at the University of Auckland in New Zealand reports that long term calcium supplementation may increase the risk for a heart attack, along with potentially increasing the risk of stroke and death. Ian Reid and colleagues did a meta-analysis encompassing several studies that tracked 12,000 elderly people over four years. Most were women, and the average age was 72. Half of them were given calcium supplements, at least 500 mg a day or more, and the other half dummy pills. There was a 30 percent increase in heart attacks in the people who were took calcium. The researchers write, "If you have 1,000 people taking calcium for five years, we expect to find 14 more heart attacks, 10 more strokes and 13 more deaths in the people given calcium than they would have had if they hadn't been treated with the mineral. That is 37 more adverse events and we expect 26 fractures being prevented. So calcium is associated with more bad things happening than with bad things prevented." It is possible that very high levels of blood calcium may damage blood vessels, contributing to hardening of arteries (atherosclerosis). When a calcium supplement is taken, the blood calcium level goes up over the following four to six hours to the top end of the normal range. This is avoided somewhat through food because the calcium from food is very slowly absorbed and so the blood calcium level changes very little. Higher blood calcium may lead to the formation of plaques in blood vessels, which can lead to heart attack, stroke and other cardiovascular diseases, BMJ, online July 29, 2010. John Baron, M.D. a professor of medicine at Dartmouth Medical School, in Lebanon, New Hampshire, was a co-author of the study.

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